EDUCATION Ph.D. 1997 Molecular Toxicology/Oncology New York University
M.S. 1994 Molecular Toxicology New York University
PROFESSIONAL EXPERIENCE September, 2005-present
Assistant Professor
Department of Pharmacology and Toxicology
College of Pharmacy
University of Arizona
Research Field: The Nrf2/Keap1 Signaling pathway
September, 1999-August, 2005
Research Assistant Professor
Biochemistry Department, University of Missouri-Columbia
Research Field: The Nrf2/Keap1 Signaling pathway
The NFkB/IkB Signaling pathway
January, 1999-August, 1999
Lecturer
Department of Biological Sciences, University of Missouri-Rolla
Courses taught: General Biology (BioSc. 110) and Virology (BioSc 391)
May, 1997-December, 1998
Postdoctoral Fellow
DuPont-Haskell Laboratories, Inhalation Toxicology, Newark, DE
Research Field: Crystalline Silica Induced Apoptosis in the Lungs of Exposed Rats
Supervisor: Dr. David B. Warheit
September, 1994-May, 1997
Graduate Research Associate
Sackler Institute of Graduate Biomedical Sciences, Department of Environmental Health Sciences
Nelson Institute of Environmental Medicine, New York University Medical Center
Dissertation: Identification and Characterization of a Novel Gene Specifically Induced by Ni2+
Thesis Advisor: Dr. Max Costa
January, 1992 – September, 1994
Graduate Research Associate
Nelson Institute of Environmental Medicine, New York University Medical Center
Master’s Thesis: Atherogenicity of Environmental Tobacco Smoke:
Molecular Mechanism of Human Arteriosclerosis
Advisor: Dr. Arthur Penn
PROFESSIONAL MEMBERSHIPS Society of Toxicology (SOT)
American Association for Cancer Research (AACR)
PATENTS
1997 Homo Sapiens NIS (Cap 43) Gene, GenBank Accession # AF004162 (also called DRg1/Ndeg1/Rit42)
TEACHING Cell communications and signal transduction* (PCOL630B)
*Course Coordinator
Case studies in Biochemical Pharmacology (PCOL820)
Pharmacy (PCOL871A)
Pharmacy (PCOL871b)
Advanced Toxicology (PCOL596C)
RESEARCH SUPPORT Grants Funded
R01 ES015010-01 (PI: Donna D. Zhang) 9/1/2006 – 8/31/2011
NIH/NIEHS Outstanding New Environmental Health Scientist Award
$2,319,477 (Total) $1,625,000 (direct)
The protective role of Nrf2 in arsenic-induced toxicity and carcinogenicity
American Cancer Society #RSG-07-154-01-CNE (PI: Donna D. Zhang) 7/1/2007-6/31/2011
$720,000 (Total) $600,000 (direct)
Regulation of the transcription factor Nrf2 by chemopreventive compounds
SWEHSC pilot research grant ES06694 (PIs: Donna D. Zhang and George Wondrak) 2006
$40,000 (direct)
Topical Nrf2-activators for skin photoprotection and chemoprevention of skin cancer