Our work on stress builds on the
observation that there are dense concentrations of stress hormone receptors
in hippocampus, and that as a consequence hippocampal function is modulated
by the levels of this hormone. We have focused on the impact of variations
in stress hormone on development and learning, with a recent interest
in the interactions between stress hormone, sleep and memory. Papers
on these topics can be downloaded below.
Kallai, J., Karádi, K., Thomas, K.G.F., Jacobs, W. J., & Nadel,
L. The role of spatial orientation disturbances in maintenances
of panic disorder with agoraphobia: Agoraphobia and the representation
of space. In A. Berthoz and J. Jouvent (eds). Anxiety and
Elsevier, Paris. (in press)
Payne, J.D. and Nadel, L. Sleep, dreams and memory consolidation: The
role of the stress hormone cortisol. Learning
and Memory, 11: 671-678, 2004.
Payne, J.D., Nadel, L., Britton, W.B. & Jacobs, W.J. The Biopsychology
of Trauma and Memory in Humans, in Reisberg, D. & Hertel, P. (Eds.),
Memory and Emotion, N.Y.: pp. 76-128, Oxford University Press, 2003.
Payne, J.D., Nadel, L., Allen, J.J.B., Thomas, K.G.F. & Jacobs,
W.J. Stress increases false memories. Memory, 10: 1-6, 2002.
Nadel, L. & Payne, J. The relationship between episodic memory
and context: Clues from memory errors made while under stress. Physiological
Research, 51 (Suppl.1): S3-S11, 2002.
Jacobs, W.J. and Nadel, L. The first panic attack. Canadian Journal
of Psychology, 53: 92-107, 1999.
Jacobs, W.J., Laurance, H.E., Thomas, K.G.F., Luczak, S.E. and Nadel,
L. On the veracity and variability of traumatic memory. Traumatology,
2: #2, 1996
Nadel, L. & Jacobs, W.J. Traumatic memory is special. Current Directions
in Psychological Science, 7: 154-157, 1998.
Jacobs, W.J. & Nadel, L. Neurobiology of reconstructed memory.
Psychology, Public Policy, and Law, 4: 1110-1134, 1998.
Nadel, L. and Jacobs, W.J. The role of the hippocampus in PTSD, panic
and phobia, In N. Kato (Ed.) Hippocampus: Functions and Clinical Relevance,
Amsterdam, Elsevier Science B.V., 1996.
Thomas, K.G.F., Laurance, H., Jacobs, W.J. and Nadel, L. Memory for
Traumatic Events: Formulating Hypotheses and Critical Experiments Traumatology,
1: #2, 1995.
Jacobs, W.J., Nadel, L. and Hayden, V.C. Anxiety disorders. In D. Stein
and J. Young (Eds.), Cognitive science and clinical disorders pp. 211-233,
San Diego: Academic Press, 1992.
Tataryn, D., Nadel, L. and Jacobs, W.J. Cognitive therapy and cognitive
science. In A. Freeman, K. Simon, L. Beutler and H. Arkowitz (Eds.)
Comprehensive handbook of cognitive therapy. New York: Plenum Press,
Nadel, L. and Willner, J. Some implications of postnatal maturation
in the hippocampal formation. In V. Chan-Palay and C. Köhler (Eds.)
The hippocampus: new vistas. New York: AR Liss, 1989.
Wilson, D.A., Willner, J., Kurz, E.M. and Nadel, L. Early experience
alters brain plasticity. Behavioural Brain Research 21: 223-227, 1986.