CAMEL Images



CAMEL Research Group, December 2008
Vipul "Six-Gun" Sheth
Byunghee "Maverick" Yoo
Julio Cardenas, a.k.a., The Mayor
Briana "Quickdraw" Bermudez
Marty "Whip" Pagel
Yuguo "Ranger" Li
 
Bruker Biospec 7T MRI scanner
Byunghee Yoo
Yuguo Li
Vipul Sheth
Julio Cardenas
Marty Pagel
 
CAMEL Chemistry Laboratory
Arizona Cancer Center
University of Arizona

 
Yb-DO3A-oAA PARACEST agent
This contrast agent has been used to detect nitric oxide and to measure pH in tumors
 
PARACEST spectra (A) and MR parametric map (B) of DEVD-(Tm-DOTA) amide before and after addition of caspase-3. The deconvoluted PARACEST spectrum of the product after reaction, showing a PARACEST effect at +8 ppm, is also shown. The parametric map shows a 14.5% decrease in water MR signal before the enzymatic reaction, and no significant change in water MR signal after reaction.
 
CAMEL Research Group, Summer 2008
Julio Cardenas
Vipul Sheth
Aswin Sundaram
Yuguo Li Byunghee Yoo
Marty Pagel

 
Measurement of Tumor pH with PARACEST MRI
 
Dynamic Contrast Enhancement MRI
DCE-MRI was used to measure changes in tumor vascular permeability before and after administering an anti-angiogenic chemotherapy.
 
Vipul Sheth Presents a Poster
at the Arizona Health Sciences Center,
University of Arizona
 
MR images and Histopathology
show infectiona nd inflammation of a mouse model
of Cystic Fibrosis after innoculation with P. aeruginosa
 
CAMEL Research Group, Summer 2007
Marty Pagel
Byunghee Yoo
Guanshu Liu
Meser Ali
Vipul Sheth
Athena Chen
Yuguo Li
Case Western Reserve University
 
Byunghee and Guanshu graduate May 2008
Guanshu Liu
Marty Pagel
Byunghee Yoo
Case Western Reserve University
 
Bruker Biospec 7T MRI scanner
and Marty Pagel,
Biological Magnetic Resonance Facility
Photo taken by Sarah Jacoby