This page is devoted to preparing an NIH R21 grant.
The title of the grant is
Surrogate Markers for Glioma Diagnosis: Diffusion Weighted
Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy
The NIH grant information is listed here.
The due date for this application is 4/10/09. However, Sponsored Projects
Services (SPS) here on campus needs to OK it on or before 4/7/09.
A current outline (pdf) of the grant can be found
here.
A current draft (pdf) of the entire grant can be found
here.
A current draft (pdf) of the specific aims can be found
here.
A current draft (pdf) of the background and significance can be found
here.
A current draft (pdf) of the preliminary studies can be found
here.
A current draft (pdf) of the research design and methods can be found
here.
A current copy (pdf) of the references are available
here.
The references for the above draft are listed here:
1: Evaluation of Cancer Therapy Using
Diffusion Magnetic Resonance Imaging
2: Changes in Water Mobility Measured by
Diffusion MRI Predict Response of Metastatic Breast Cancer to
Chemotherapy
3: Diffusion-Weighted Imaging of
Radiation-Induced Brain Injury for Differentiation from Tumor Recurrence
4: RECURRENT GLIOMA AND RADIATION INJURY USING
MAGNETIC RESONANCE SPECTROSCOPY IN COMBINATION WITH DIFFUSION-WEIGHTED IMAGING
5: Survival and prognostic factors of patients
with unresectable glioblastoma multiforme
6: Relationship of glioblastoma multiforme to
the lateral ventricles predicts survival following tumor resection
7: MR spectroscopy in the evaluation of
recurrent contrast-enhancing lesions in the posterior fossa after tumor
treatment
8: Sulci density map to aid in use of
apparent diffusion coefficient for therapy evaluation
9: Advanced MRI of Adult Brain Tumors
10: New Guidelines to Evaluate the Response to Treatment
in Solid Tumors
11: Response Criteria for Phase II Studies of
Supratentorial Malignant Glioma
12: Pseudoprogression in Glioblastoma
13: Malignant Gliomas: MR Imaging Spectrum of
Radiation Therapy- and Chemotherapy-induced Necrosis of the Brain after
Treatment
A glossary of NIH terms can be found here.