Dr Fernando L Mendez

Postdoctoral Research Associate

University of Arizona

 

 

The Hammer Lab

Arizona Research Labs

 

 

 

CONTACT DETAILS

University of Arizona

Room 228 Biological Sciences West

1041 E Lowell St

Tucson, AZ, 85721

 

Lab: 520-626-0404

E-mail: flmendez@email.arizona.edu

 

FLM

 

CURRENT STATUS AND INTERESTS

 

My current appointment is Postdoctoral Fellow in the Bustamante Lab at Stanford University.

 

My major interests are theoretical, statistical and methodological aspects of population genetics, especially as applied to humans. My main topic of interest is population admixture, with particular interest in archaic admixture and adaptation following admixture. I am also interested in the effects of natural selection in assessments of global genetic variation.

 

PEER REVIEWED PUBLICATIONS

 

Mendez, F.L., Veeramah, K.R., Thomas, M.G., Karafet, T.M., Hammer, M.F. Reply to 'The 'extremely ancient' chromosome that isn't by Elhaik et al' . (2014) EJHG in press.

 

Karafet, T.M., Mendez, F.L., Sudoyo, H., Lansing, J.S., Hammer, M.F. Improved phylogenetic resolution and rapid diversification of Y-chromosome haplogroup K-M526 in Southeast Asia. (2014) EJHG - advance online publication.

 

Mendez, F.L., , Krahn, T., Schrack, B., Krahn, A.-M., Veeramah, K.R., Woerner, A.E., Forka Leypey Mathew Fomine, Bradman, N., Thomas, M.G., Karafet, T.M., Hammer, M.F. An African American paternal lineage adds and extremely ancient root to the human Y chromosome phylogenetic tree . (2013) AJHG 92:454-459.

 

Mendez, F.L., Watkins, J.C., Hammer, M.F. Neandertal origin of genetic variation at the cluster of OAS immunity genes . (2013) Mol Biol Evol 30(4):798-801.

 

Mendez, F.L., Watkins, J.C., Hammer, M.F. A haplotype at STAT2 introgressed from Neandertals and serves as a candidate of positive selection in Papua New Guinea . (2012) AJHG 91:265-274.

 

Mendez, F.L., Watkins, J.C., Hammer, M.F. Global genetic variation at OAS1 provides evidence of archaic admixture in Melanesian populations . (2012) Mol Biol Evol 29(6):1513-1520. Supp.Mat.

 

Veeramah, K.R, Wegmann, D, Woerner, A, Mendez, F.L., Watkins, J, Destro-Bisol, G, Soodyall, H, Louie, L, Hammer, M.F. An early divergence of KhoeSan ancestors from those of other modern humans is supported by an ABC-based analysis of autosomal re-sequencing data. (2012) Mol Biol Evol 29(2):617-30 .

 

Hammer, M.F. Woerner, A.E., Mendez, F.L., Watkins, J.C., Wall, J.D. Genetic evidence for archaic admixture in Africa. (2011) PNAS 108(37):15123-7

 

Mendez, F.L. Karafet, T.K., Krahn, T., Ostrer, H., Soodyall, H., Hammer, M.F. Increased resolution of Y chromosome haplogroup T defines relationships among populations of the Near East, Europe, and Africa. (2011) Hum Biol.83(1):39-53 Supp. Mat.

 

Hammer, M.F., Woerner, A.E., Mendez, F.L., Watkins, J.C., Cox, M.P., Wall, J.D. The ratio of human X chromosome to autosome diversity is positively correlated with genetic distance from genes. (2010) Nat Genet 42(10):830-1

 

Hammer. M,F., Behar, D.M., Karafet, T.M., Mendez, F.L., Hallmark, B., Erez, T., Zhivotovsky, L.A., Rosset, S., Skorecki, K. Extended Y chromosome haplotypes resolve multiple and unique lineages of the Jewish priesthood. (2009) Hum Genet 126(5):707-17

 

Hammer, M.F., Mendez, F.L., Cox, M.P., Woerner, A.E., Wall, J.D. Sex-biased evolutionary forces shape genomic patterns of human diversity. (2008) PLoS Genet 4(9):e1000202

 

Wall, J.D., Cox, M.P., Mendez, F.L., Woerner, A., Severson, T., Hammer, M.F.A novel DNA sequence database for analyzing human demographic history. (2008) Genome Res 18(8):1354-61

 

Karafet, T.M., Mendez, F.L., Meilerman, M.B., Underhill, P.A., Zegura, S.L., Hammer, M.F. New binary polymorphisms reshape and increase resolution of the human Y chromosomal haplogroup tree. (2008) Genome Res 18(5):830-8

 

Cox, M.P., Mendez, F.L., Karafet, T.M., Pilkington, M.M., Kingan, S.B., Destro-Bisol, G., Strassmann, B.I., Hammer, M.F. Testing for archaic hominin admixture on the X chromosome: model likelihoods for the modern human RRM2P4 region from summaries of genealogical topology under the structured coalescent. (2008) Genetics 178(1):427-37

 

Pilkington, M.M., Wilder, J.A., Mendez, F.L., Cox, M.P., Woerner, A., Angui, T., Kingan, S., Mobasher, Z., Batini, C., Destro-Bisol, G., Soodyall, H., Strassmann, B.I., Hammer, M.F. Contrasting signatures of population growth for mitochondrial DNA and Y chromosomes among human populations in Africa. (2008) Mol Biol Evol 25(3):517-25.

 

2003-2011

University of Arizona (UofA), Tucson,

PhD Studies,

Major Department of Ecology and Evolutionary Biology .

Minor Department of Mathematics .

Dissertation title Archaic Introgression and Natural Selection in the Evolution of Modern Humans: A study of genetic variation at the loci containing the genes OAS1 and STAT2

Advisor: Professor Michael F Hammer

Minor Advisor: Professor Joseph C Watkins

1997-2000

Universidad de Cuyo (Instituto Balseiro), Bariloche,

Physics

1995-1996

Universidad de Buenos Aires, Buenos Aires

Physics

 

 

EMPLOYMENT HISTORY

           

2011-present

University of Arizona, AZ 85721

Position: Postdoctoral Research Associate

2007-2011

University of Arizona, Tucson (UofA), AZ 85721

Position: Graduate Associate, Department of Ecology and Evolutionary Biology and Arizona Research Laboratories

2003-2007

University of Arizona (Uof A), Tucson

Position: Graduate Assistant

2001-2002

University of Buenos Aires (UBA), Buenos Aires

Position: Ayudante de 1ra (Graduate Assistant)


TALKS

2nd Cornell Probability Summer School, "Linear tests of the site frequency spectrum", Cornell, Ithaca, NY, June 2006

Young Investigators in Population Genetics , "Identifying the timing and strength of selection to test specific hypotheses in human evolution", University of Arizona (2008)

Quantitave Biology Colloqium, “Genetic signatures of archaic introgression in modern humans" , University of Arizona (2012)


RELATED PROFESSIONAL EXPERIENCE

 Reviewer for Genetica, Molecular Biology and Evolution, and Bioinformatics


AWARDS

 Full Scholarship (Aug 1997-Dec 2000) granted by Comision Argentina de Energia Atomica (Argentinian Atomic Energy Commission)


TEACHING EXPERIENCE

From 2003 to 2008 I worked as Teaching Assistant in the Department of Ecology and Evolutionary Biology of the University of Arizona

In 2001-2002 I lectured on several courses in Mathematics, including Linear Algebra and Calculus.


OTHER SKILLS

Experience in laboratory techniques, including PCR design, DNA sequencing and genotyping.

Development of statistical methods applied to population genetics

Experience implementing analytical methods in the programming languages C, PERL, and R.


LANGUAGES

English: read, write and talk (fluent)

Spanish: read, write and talk (fluent, first language)

Italian: read and talk (basic)

French: read (basic)


COLLABORATORS AND FRIENDS

Michael F. Hammer, Arizona Research Laboratories, University of Arizona

Joseph C. Watkins, Department of Mathematics, University of Arizona

Murray P. Cox, Institute of Molecular Biosciences, Massey University

Heather L. Norton, Department of Anthropology, University of Cincinnati

Krishna Veeramah, Arizona Research Laboratories, University of Arizona

Tatiana Karafet, Arizona Research Laboratories, University of Arizona

Julian Mendez, Institute for Theoretical Computer Science, Dresden Institute of Technology

 

 

Last updated : 2014/07/17