Dr. Amrit Mandal
My research interest is to understand the cellular ion transport mechanisms by different transporters (Na/H Exchangers, Na,K-ATPase, sodium calcium exchanger etc.) in optic nerve head astrocytes and in lens epithelial cells to understand the general cellular signaling events as well as initiation and progression mechanisms of different diseases like glaucoma and cataract with an eventual goal of developing therapeutics to control these diseases. Src family kinases (SFKs) are very much important in modifying Na,K-ATPase activity in different cell types. My research is focused to find SFK phosphorylation-activation mediated downstream effects in cellular sodium, proton and calcium transport.